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🧪 Experimental Design

🔬 Clinical Trials

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Trial Search

Current Search Criteria:

Intervention: therapy with disease-modifying anti rheumatic drugs (DMARD)

Found 114 matching trials

A Study to Compare Subcutaneous Versus Intravenous Administration of RoActemra/Actemra (Tocilizumab) in Participants With Moderate to Severe Active Rheumatoid Arthritis

PHASE3

This randomized, double-blind, parallel group study compares the efficacy a...

Status

Completed

Location

Multiple Locations

Start Date

2010-09

Trial ID

NCT01194414

Treatments Being Tested

tocilizumab SC tocilizumab IV placebo to tocilizumab SC placebo to tocilizumab IV Disease-modifying antirheumatic drugs (DMARDs)

A Study to Assess Safety and Efficacy of ASP015K in Participants With Rheumatoid Arthritis (RA) Who Had an Inadequate Response or Intolerance to Methotrexate (MTX)

PHASE3

The purpose of this study is to verify the superiority of ASP015K in combin...

Status

Completed

Location

Site CN00048

Start Date

2018-09-27

Trial ID

NCT03660059

Treatments Being Tested

Peficitinib Plaebo Disease-modifying antirheumatic drugs (DMARDs)

Canadian Humira Post Marketing Observational Epidemiological Study: Assessing Effectiveness in Ankylosing Spondylitis

N/A

The current study will assess the real - life effectiveness of adalimumab i...

Status

Completed

Location

Rheumatology Clinic /ID# 54768

Start Date

2011-06-29

Trial ID

NCT01387802

Comparing The Effectiveness And Safety Of 2 Doses Of An Experimental Drug, CP-690,550, To Methotrexate (MTX) In Patients With Rheumatoid Arthritis Who Have Not Previously Received MTX

PHASE3

This study is designed to compare the effectiveness of the experimental dru...

Status

Completed

Location

Catalina Pointe Clinical Research, Inc.

Start Date

2010-01

Trial ID

NCT01039688

Treatments Being Tested

CP-690,550 CP-690,550 Disease-modifying antirheumatic drug

A Study of Tocilizumab (RoActemra/Actemra) in Monotherapy or in Combination With Methotrexate or Other Non-Biologic DMARDs in Participants With Active Rheumatoid Arthritis and an Inadequate Response to Current Non-Biologic DMARD Therapy or the First Anti-TNF Biologic Agent

PHASE3

This open-label study will evaluate the efficacy and safety of tocilizumab ...

Status

Completed

Location

Aberdeen Royal Infirmary

Start Date

2014-03-04

Trial ID

NCT02046603

Treatments Being Tested

Tocilizumab DMARDs Oral Corticosteroids Methotrexate

CHronic Nonbacterial Osteomyelitis International Registry

N/A

The objective of the study is to establish a prospective disease registry f...

Status

Recruiting

Location

Seattle Children's Hospital

Start Date

2018-08-01

Trial ID

NCT04725422

Treatments Being Tested

Methotrexate Sulfasalazine Leflunomide Pamidronate Zoledronic acid Etanercept Adalimumab Certolizumab Infliximab Golimumab NSAID

To Evaluate The Safety of SAR153191 (REGN88) and Tocilizumab Added to Other RA Drugs in Patients With RA Who Are Not Responding to or Intolerant of Anti-TNF Therapy (SARIL-RA-ASCERTAIN)

PHASE3

Primary Objective: To assess, in the same study, the safety of sarilumab a...

Status

Completed

Location

Investigational Site Number 840152

Start Date

2013-03

Trial ID

NCT01768572

Treatments Being Tested

sarilumab SAR153191 (REGN88)tocilizumab hydroxychloroquine methotrexate sulfasalazine leflunomide subcutaneous placebo intravenous placebo

A Study of Clinical and Immune Responses to Sequential Biologic Therapies in Psoriatic Arthritis

N/A

The goal of this observational study is to evaluate how well advanced thera...

Status

Not Yet Recruiting

Location

Royal United Hospitals Bath NHS Foundation Trust

Start Date

2026-06

Trial ID

NCT07417995

Treatments Being Tested

Biologic or targeted synthetic DMARD (b/tsDMARD)

The SetPoint System Safety & Performance Post-Approval Study

N/A

Prospective, multicenter, post-market, registry study designed to systemati...

Status

Not Yet Recruiting

Location

Multiple Locations

Start Date

2026-04-15

Trial ID

NCT07489326

Treatments Being Tested

SetPoint System

Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Ankylosing Spondylitis Who Have an Inadequate Response to Biologic Disease-Modifying Antirheumatic Drug Therapy

PHASE3

The primary objective of this study is to evaluate the effect of filgotinib...

Status

Withdrawn

Location

Multiple Locations

Start Date

2020-12

Trial ID

NCT04483687

Treatments Being Tested

Filgotinib Placebo to Match Filgotinib

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